Welcome to the Wu Lab
at Scripps Research
Our Lab at Scripps Research, Department of Molecular and Cellular Biology, focuses on integrating synthetic chemistry with glycobiology to explore the cellular and molecular mechanisms that control immune responses toward cancer and human pathogens. Our website is designed to provide valuable insights into our research, publications, and news updates. We welcome you to explore the world of glycobiology and its implications in immunology and cancer research.
Our Research Focus
In the Wu Lab, we are dedicated to unraveling the intricate connections between synthetic chemistry and glycobiology. Our team explores the fascinating interplay of cellular and molecular mechanisms that dictate immune responses targeting cancer and human pathogens. Through our collaborative efforts and cutting-edge research, we strive to make significant contributions to the fields of immunology and cancer research. Join us in our journey to decode the complexities of glycobiology and its profound impact on human health.
Latest News & Events
 Commencement 2025Scripps held the 33rd commencement on Friday. Had two very talented students that graduated. Eleanor Bashian, a joint student with the Paulson lab, discovered that selective removal of Siglec-E ligands via the crispr-mediated KO the enzyme responsible for the creation of Siglec ligands on CD8 T cells can significantly enhance their anti-tumor immunity in multiple mouse solid tumor models by improving CD8⁺ T cell differentiation, tumor infiltration, and cytotoxicity. |  Commencement 2025Yujie Shi, who came to my lab with high recommendations from Prof. Xing Chen, was a key member of the team that developed FucoID. She demonstrated for the first time that we can use this technique to isolate antigen-specific T cells from human cancer patients in collaboration with the Gutkind lab at UCSD. She also developed a method to uncouple T cell proliferation from differentiation, allowing for the generation of large numbers of stem-like T cells suitable for infusion. Congratulations! |  Ellie's defense |
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 Ellie's defense party |  Congratulations Dr. Bashian! |  Ellie's defense party |
 Yujie's dissertation defense |  Yujie's defense party |  Celebration dinner for Dr. Shi and Dr. Bashian |
 Congratulations Dr. Shi! |  Yujie's defense party |  Summer Pizza PartyWu Lab celebrates our summer interns with a pizza party! |
 Welcome rotation students!Dr. Wu cooks dinner with two rotation students and an intern. |  Yingqin HouStaff scientist Yingqin has published her paper in Cancer Immunology Research. Congratulations! |  Dr. Wu delivers lectureDr. Wu visited Institut Pasteur to speak about recent research from the lab. |
